Recently published in the journal Science, Public Health Policy, and the Law, Jessica Rose, PhD, MSc, BSc, authored a report titled, “A Report on the U.S. Vaccine Adverse Events Reporting System (VAERS) of the COVID-19 Messenger Ribonucleic Acid (mRNA) Biologicals,” reminding the reader of the importance of safety associated with any “technologically novel” biologic therapy or vaccine still in some form of the experimental stage. The COVID-19 vaccines developed in the United States and Germany transcended any vaccine development efforts before—their compelling, effective, and according to health authorities, safe vaccines now help nations around the world combat COVID-19. The author analyzes the VAERS database and compares the number of COVID-19 versus flu vaccine safety reports. Using vaccine data up to April 10, 2021, Dr. Rose shares with the reader that by the end of March, about 100X more COVID-19 vaccinations occurred as opposed to flu vaccinations. Hence perhaps not surprising that 380 times more safety reports were generated due to COVID-19 inoculations. Thus 99% of all adverse events (AEs) recorded in VAERS are associated with the mass COVID-19 vaccination program. The researcher brings a methodical approach to the review of the VAERS database and identifies significant safety signals. On the other hand, not factored in are the risks of no vaccination—e.g. the scenario if there were no vaccinations. How many more deaths, illnesses, and long-term COVID cases would accrue? TrialSite reminds all of the Cleveland Clinic study, indicating that 99%+ of those hospitalized from January to mid-April 2021 were unvaccinated. The point is that all of the risks must be considered, analyzed, and ultimately calculated for a true depiction of actual risk that will gain public policy attention.