Comment:  We all know social isolation is a serious stressor but there do not appear to be many studies that quantify its impact.  Here are two studies that do.  The impact clearly differs among groups.  But functionally, children kept out of school, teens kept from seeing each other, college students kept from college and social activities, elders isolated from contact, extroverts of all kinds, and families or social groups separated from each other are some of the stress points.  Just as the economic impact of covid may rival its direct medical effect, so may social isolation.  We can think of covid as a trifecta stressor — the virus itself, the economic and the social impact.  that multiplier is far bigger than the number of reported cases.  call it the CMI — the Covid Misery Index.
which is why the undervaluation of integrative health interventions and the slowness of the system to truly evaluate controversial treatments raise concerns.

Studies Reveal Detrimental Impact of Social Isolation and Quarantine Throughout the COVID-19 Pandemic

May 26, 2021 European Society of Endocrinology

Studies reveal that social isolation and quarantine throughout the COVID-19 pandemic may have a detrimental impact on people living with pre-existing conditions.

Social isolation and quarantine can have a detrimental impact on physical and mental health of people living with pre-existing conditions, according to two studies being presented at the 23rd European Congress of Endocrinology (e-ECE 2021) on Wednesday 26 May at 14:14 CET.

The studies bring together research on the impact of social isolation and quarantine for people living with diabetes in the Adjara Region of Georgia, and on patients with hypocortisolism in Italy. Both studies reported that social isolation during the pandemic caused significant psychological and/or physical distress on the observed individuals.

Data from the first study revealed that the impact of quarantine on people living with diabetes in the Adjara Region caused blood pressure (BP) levels to increase in 88.2% of patients with 50% of these cases resulting in high BP hospitalization. In addition to these physical factors, increased feelings of anxiety and fear were observed on 82% of patients. In the second study, patients with hypocortisolism experienced increased anxiety and depression, associated with a dissatisfaction feeling of self and a reduced resiliency, when compared with Italian healthy controls. As these are all contributing factors to overall health deterioration, these findings suggest further research is required to allow patients with pre-existing conditions to remain fit and healthy during the current pandemic.

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